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Natural Bone Ingrowth with EIT Cellular Titanium®

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Learn more about our EIT Cellular Titanium®. The state of the art porous titanium cages facilitate a fast and anatomical balanced fusion process. more...

EIT Cellular Titanium® Cages  

EIT Cellular Titanium® in combination with anatomical landmarks, to achieve an anatomical restoration of the spinal segment, has been applied in a family of cervical and lumbar cages. more...

EIT Emerging Implant Technologies Announces 510(k) Approval from the FDA for Full 3D Printed Cage Portfolio and Begins Commercialization Process in the United States.   

Emerging Implant Technologies GmbH (EIT), a German medical device manufacturer exclusively focused on creating innovative technologies for spinal application by utilizing additive manufacturing, announces that it has received full approval from the FDA to commercialize its spinal interbody product offerings for ALIF, TLIF, PLIF and Cervical procedures as of July 11th  2017.

Preliminary results of EFFECT Trial presented at SSA 2017

Preliminary results of quantitative functional X-Ray analysis of stand-alone interbody 3-D printed porous titanium cervical implants

Mark P. Arts MD PhD, Jasper F.C. Wolfs MD, Department of Neurosurgery, Haaglanden Medical Center, The Hague, the Netherlands

Introduction: Anterior cervical discectomy and fusion (ACDF) is a common procedure in cervical spine surgery. Literature describes a wide range in fusion percentages and presently, there is no golden standard for the measurement of fusion in spine surgery. Analysis of dynamic X-rays of the cervical spine result in a very accurate and reliable measurement of fusion. The present report describes the preliminary 3, 6 and 12 months Functional X-ray Analysis (FXA) of stand-alone 3-D printed porous titanium cervical implants (EIT GmbH).

Methods: A prospective cohort study of 50 patients with single level ACDF using a 3-D printed titanium cervical cage (EFFECT trial) was performed. The fusion rates were compared to 50 patients treated with PEEK cages from a previous randomized controlled trial (CASCADE trial.) The results of the first 10 patients of the EFFECT trial are shown in this abstract. Flexion and extension X-ray data on 3, 6 and 12 months (N=10) were analyzed using FXA (Aces GmbH, Leipzig) to determine RoM (in °) of the operated level and subsidence (in mm). The results were compared to historical quantitative motion analysis and subsidence data from the CASCADE Trial.

Results: The mean RoM of the EIT implants after 3 months was 2.8° (SD 1.9°), 2.7° (SD 2.2°) after 6 months, decreasing to 1.5° (SD 1.7°) after 12 months. Subsidence was < 2 mm in all patients. At every time frame, the lack of motion was more prominent in the porous titanium cage compared to the PEEK implants from the CASCADE Trial. Moreover, the subsidence rate was less in the porous titanium implants.

Conclusion: These preliminary functional X-ray results of the porous titanium cervical implants are very promising regarding RoM, fusion and subsidence rate. The results of the complete EFFECT trial date are needed to support the superiority of porous titanium implants. 

EIT in the Press: Start-up to Watch

EIT is betting on a highly experienced management team with extensive networks and commercial experience to stay ahead of the curve in the increasingly active field of 3D-printing spinal implants, which offer the potential to manufacture complex, improved implants affordably. Read the full article recently published in MedTech STRATEGIST.

Impressive 6 and 12 months fusion pattern
Recently, we described in two white papers the imaging characteristics and fusion pattern of EIT cervical and lumbar implants. In these papers we present a series of cases typical for a spinal center employing the use of EIT Cellular Titanium® implants. The images in the white papers demonstrate bone ingrowth, sagittal restoration and clear imaging in CT and MRI in all cases with a sufficiently long follow-­up, with no adverse effects observed.
In this news item you can find an example of CT images of a TLIF case described in the lumbar paper. The postoperative image demonstrates some devoid implant-endplate contact, which has been filled up within 6 months postoperative. Besides the bone ingrowth, also the development of a trabecular pattern according to 'Wolf's law' in the cancellous bone of the vertebral body is a sign of the bioactivity of the implants, being accurately integrated in the biomechanical construct.
EIT Lunchworkshop EuroSpine 2015 ON-DEMAND WEBINAR 

In this lunchworkshop three top-speakers, being Prof. H. Michael Mayer, MD PhD, Jasper F. Wolfs, MD, Dr. Steven M. van Gaalen, MD PhD,  have discussed the issues with current standard cage materials and designs, which can be overcome using porous 3-D printed EIT Cellular Titanium® cages. By watching the on demand webcast, you will be brought up to speed with the current status of EIT patient specific implants and the results of the cervical and lumbar clinical applications.